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Wave Life Sciences

Medicinal Chemistry Co-op

1w

Wave Life Sciences

Cambridge, US · Internship · $65,000 – $85,000

About this role

Wave Life Sciences is a biotechnology company focused on unlocking the broad potential of RNA medicines to transform human health. Our RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics. Our diversified pipeline includes clinical programs in Duchenne muscular dystrophy, Alpha-1 antitrypsin deficiency, Huntington’s disease, obesity and a preclinical program in NASH/MASH.

Wave Life Sciences seeks a highly motivated, energetic, safety conscious and results-driven candidate to join its team of medicinal chemists. The co-op’s role will primarily consist of laboratory work in support of the medicinal chemistry team’s efforts. The candidate will plan, design and execute multi-step synthesis including purification and compound characterization.

The candidate will analyze raw materials and final products received and maintain records. Training will be provided in a variety of laboratory techniques and instrumentation including NMR, UPLC/MS, polarimeter, Isco column chromatography and benchtop rotovap. These efforts support the development of novel nucleic acid therapies across multiple disease areas.

Join a collaborative team driven by the calling to “Reimagine Possible” in a multidisciplinary environment. Present data and summarized results both orally and in written form within team meetings. This position offers an excellent learning opportunity in cutting-edge science.

Requirements

  • Working towards a Bachelor’s degree in chemistry or a related discipline (biochemistry, chemical engineering)
  • Successfully completed Organic Chemistry courses (I and II or equivalent) with lab
  • At least two years of undergraduate education completed within a Chemistry discipline preferred
  • Excellent oral and written skills
  • Superior organizational and time management skills
  • Collaborative and self-motivated team player
  • Enthusiasm and excitement for the pursuit of cutting-edge science
  • Organic and biochemistry lab experience preferred

Responsibilities

  • Perform multi-step organic synthesis and isolate newly synthesized chemical compounds
  • Analyze chemical compounds through various analytical techniques (UV-Vis, LC/MS, Polarimeter, NMR) and interpret experimental outcomes
  • Troubleshoot and optimize reaction protocols based on discussions with supervisor
  • Take detailed notes about experimental design and conditions
  • Record experimental results in both electronic notebook and presentation format
  • Present data and summarized results both orally and in written form within multidisciplinary team meetings
  • Plan, design and execute multi-step synthesis including purification and compound characterization

Benefits

  • Equal employment opportunities (EEO) without regard to race, color, religion, sex, national origin, age, disability or genetics
  • Complies with applicable state and local laws governing nondiscrimination in employment