Postdoctoral Research Associate - Chemical Biology & Therapeutics

4w4 weeks ago

St. Jude Children's Research Hospital

Memphis, US · Full-time · $72,500 – $72,500

About this role

A postdoctoral position is immediately available in the laboratory of Dr. Jordan Meier aimed at defining the functional consequences of site-specific RNA modifications using engineered in vitro transcription platforms. This research sits at the crossroads of chemical biology and RNA biochemistry.

Work will involve solid-phase transcription, preparation of regionally modified mRNAs, and functional characterization of modified transcripts. A background in RNA biochemistry or nucleic acid synthesis is preferred for these experimental procedures.

St. Jude Children’s Research Hospital is a world-class institution dedicated to pediatric cancer. It is the first NCI-designated Comprehensive Cancer Center devoted solely to children. The 300 faculty work in a highly collaborative multidisciplinary environment, including a Nobel laureate and members of the National Academies.

Postdoctoral trainees at St. Jude benefit from a blend of academic freedom and industrial efficiency, with access to shared resources and cutting-edge technology. Customized professional and career growth programs, including grant writing workshops and non-research career advancement, are designed to enhance career readiness.

Requirements

PhD in Chemical Biology, Biochemistry, or a related field.
Background in RNA biochemistry or nucleic acid synthesis.
Experience with solid-phase transcription and in vitro transcription platforms.
Proficiency in preparation of regionally modified mRNAs.
Experience with functional characterization of modified transcripts.
Ability to work collaboratively in a multidisciplinary research environment.
Strong organizational skills for maintaining detailed experimental records.

Responsibilities

Define the functional consequences of site-specific RNA modifications using engineered in vitro transcription platforms.
Perform solid-phase transcription to generate modified RNA transcripts.
Prepare regionally modified mRNAs for functional characterization.
Conduct functional characterization assays to assess the impact of RNA modifications.
Utilize chemical biology approaches to investigate RNA modification biology.
Collaborate with interdisciplinary team members to integrate findings.
Maintain accurate experimental records and contribute to scientific publications.

Benefits

Competitive salary starting at $72,500 per year.
Generous relocation assistance.
Comprehensive benefits package.
Customized professional and career growth programs including grant writing workshops and a professional development allowance.
Access to shared resources and cutting-edge technology led by expert scientists.
A vibrant postdoc community that fosters connections and well-balanced life.