Director, Process Engineering & Packaging

4w1 month ago

AstraZeneca

Cambridge, GB · Full-time · £120,000 – £160,000

About this role

Join AstraZeneca Biologics as a Process Engineering & Packaging Leader and drive innovation in biopharmaceutical process development and technology transfer across UK and EU operations. This role develops early and late-stage clinical fill/finish processes, combination product assembly processes, and packaging for the biologics portfolio.

You will lead a high-impact team of scientists and engineers, bringing scientific rigour, practical innovation, and deep collaboration to sophisticated challenges. Day-to-day, you will oversee the process development of diverse biopharmaceutical dosage forms, including liquid and lyophilized formulations, novel drug delivery formulations, and drug delivery devices.

This position requires effective collaborative interactions with AstraZeneca Biologics and Global Biological Operations leaders, as well as internal and external manufacturing sites. You will build and maintain world-class technical capabilities while fostering a supportive community that values kindness alongside ambition.

In this pivotal role, you will elevate design for manufacturability, technology transfer, and packaging readiness to enable seamless scale-up across a global network. The opportunity to lead groundbreaking process development for a diverse biologics portfolio offers significant professional growth and impact.

Requirements

Experience leading a team responsible for process development and packaging for clinical products
Experience developing robust drug product and device assembly processes for commercial production in collaboration with Operations
Experience working with late-stage formulation development, device development, clinical operations, supply chain, quality, and regulatory functions
Ability to lead a sophisticated scale-down fill/finish development lab
Proven ability to provide technical support for clinical and commercial production
Strong collaborative skills to work effectively with AstraZeneca Biologics and Global Biological Operations leaders
Experience with diverse biopharmaceutical dosage forms including liquid and lyophilized formulations, nanoparticles, and high concentration formulations

Responsibilities

Provide technical and strategic leadership for the development of drug product and device assembly processes, including design for manufacturability
Oversee development and technical support of clinical and commercial fill-finish processes, clinical packaging development, and commercial packaging support
Lead technology transfer to both internal and outsourced commercial manufacturing sites across the global network
Lead and manage a technical team of 8-10 scientists and engineers, including resource management, prioritisation, and critical assessment of technical work
Apply scientific and engineering knowledge and tools to issues and problems arising during development and execution of manufacturing processes
Maintain a strong technical culture and establish strong working relationships at internal and external interfaces
Lead, mentor, and develop high-performing teams whilst building world-class technical capabilities
Effectively lead in a matrix environment and influence broadly internally and externally

Benefits

Hybrid working model with 4 days per week on-site at Cambridge Biomedical Campus
Opportunity to lead groundbreaking process development for a diverse biologics portfolio
Supportive community that values kindness alongside ambition
Chance to build and maintain world-class technical capabilities