Staff / Senior Staff Bioinformatics Data Scientist

6w1 month ago

Rezo Therapeutics

San Francisco, US · Full-time · $180,000 – $260,000

About this role

Rezo Therapeutics is a different kind of biopharma company. Our mission is to dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated network biology platform that will redefine our understanding of human disease and ability to treat it.

We are hiring at the Staff / Senior Staff level for a Bioinformatics Data Scientist to join the Computational Biology and AI Team. In this role you will collaborate with an interdisciplinary group combining genetics, proteomics and structural biology to tackle challenging biological questions and develop transformative therapies.

Located in San Francisco’s vibrant Mission Bay neighborhood, Rezo fosters a workplace of collaboration, respect and diversity. You will combine deep expertise and statistical rigor in analyzing biological data with the ability to communicate clearly to biological and computational audiences.

Joining Rezo at this stage provides an opportunity to make a meaningful impact in a fast-paced environment. The impact of your work will extend beyond building tools to directly influence therapeutic program decisions.

Requirements

PhD in computational biology, bioinformatics, systems biology, cancer biology or related field with 8+ years of industry experience.
Deep experience analyzing at least three of the following -omic datasets: transcriptomics, proteomics and their variants, AP-MS / interactomic data and functional genomics.
Strong python engineering skills with comfort working in a shared codebase and using software engineering best practices including code reviews.
Clear demonstrations of the ability to take a biological question from raw data to a concrete mechanistic or translational conclusion.
Working fluency in cancer biology, including oncogenic signaling, tumor suppressors, cell cycle and the use of biomarker classification to distinguish sensitive versus resistant populations.
Proven ability to work independently while fostering collaboration in a team environment.
Excellent organizational, communication, and interpersonal skills.

Responsibilities

Design and implement analyses across Rezo’s protein network datasets, refining existing approaches and developing new methods as needed.
Integrate multi-omics data to build mechanistic and translational understanding of our programs, spanning from mechanism of action to patient biomarker selection strategies.
Build internal tools and interfaces that enable the rest of the company to explore the data and make decisions based on conducted analyses.
Apply ML methods, including interpreting results and curating data for ML methods.
Communicate results clearly in writing, figures and presentations so that the analyses can be translated into program decisions.