Principal Technical Project Manager

4w1 month ago

Genomics England

London, GB · Full-time · £77,000 – £77,000

About this role

Genomics England is a global leader in enabling genomic medicine and research, focused on creating a world where everyone benefits from genomic healthcare. We support the NHS's world-first national whole genome sequencing service and run the growing National Genomic Research Library.

We are seeking a Principal Technical Project Manager to help deliver and enhance modern on-premise and cloud-based infrastructure supporting world-leading genomics diagnostics and research. In this role, you will work closely with the Scalable Service Lead and leadership team to guide multiple interdependent technical workstreams.

You will collaborate across squads, suppliers, and partners while supporting the Service Owner in coordinating technical platform delivery and managing third-party contributions. This senior role suits someone with strong technical understanding and excellent stakeholder engagement skills.

You will have the opportunity to work on major genomics initiatives that connect research and clinical care at national scale, enabling immediate healthcare benefits and advances for the future. Our mission is to secure the UK's position as the best place to discover, prove and benefit from genomic innovations.

Requirements

Project, risk, and issue management with a proactive and solutions-focused approach.
Strong technical understanding of on-premise and cloud-based infrastructure.
Excellent stakeholder engagement skills with experience managing third-party contributions.
Experience delivering complex platforms in regulated or data-intensive environments.
Collaborative and inclusive approach to delivery, with ability to build positive relationships.
Experience with governance frameworks, PMO standards, and programme-level reporting.
Ability to manage escalations constructively and facilitate respectful conflict resolution.

Responsibilities

Lead end-to-end delivery of key technical areas within the programme, taking ownership while fostering a collaborative, supportive delivery environment.
Partner with the Product Manager and/or Service Owner to validate and agree requirements, ensuring alignment with timelines, budgets, and OKRs.
Establish and maintain delivery plans, tracking progress and communicating clearly where adjustments or support are needed.
Proactively identify and resolve issues, working closely with teams to remove blockers and enable successful outcomes.
Create and manage RAID logs, regularly reviewing and coordinating follow-up actions.
Produce clear, concise status updates and contribute to programme and board-level reporting where required.
Support structured and inclusive decision-making processes, ensuring the right stakeholders are engaged at the right time.
Apply appropriate governance to meet internal and external standards, including cybersecurity, data protection, data quality, and regulatory requirements.