Senior Director, US Market Access

1w1 week ago

Mirum Pharmaceuticals

Foster City, US · Full-time · $280,000 – $315,000

About this role

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. The Senior Director of U.S. Market Access shapes and elevates U.S. market access strategy to drive optimal coverage, pricing, and patient access across the portfolio and future assets. This role ensures innovation translates into real-world patient access with purpose and urgency.

Lead critical access decisions end-to-end, owning pricing strategy, payer positioning, and execution with high autonomy. Challenge the status quo by introducing insight-driven approaches rooted in real-world payer dynamics and behavior. Translate clinical and economic evidence into practical, payer-ready tools that influence coverage and reimbursement.

This highly cross-functional role partners across Commercial, Medical, Patient Services, Government Pricing, Legal/Compliance, and Supply Chain. Act as the enterprise voice of access, influencing brand strategy, pricing, and commercialization planning. Align with the US Head of Payer Accounts on strategic planning and escalations.

Blend strategic vision with operational experience and deep payer expertise for rare disease patients. Operate grounded in values: Care, Be Real, Get it Done, Have Fun. Join a collaborative team advancing scientific discoveries into important medicines amid a growing portfolio and pipeline.

Requirements

Bachelor’s degree required; MBA or advanced degree preferred
10+ years of experience in market access, payer marketing, or reimbursement, with rare disease experience strongly preferred
Proven success in launching and managing access for rare disease products
Deep payer expertise in competitive rare disease markets including UM criteria and specialty pharmacy distribution
Experience owning pricing strategy, payer positioning, and execution
Strong cross-functional leadership across commercial, medical, and legal teams
Knowledge of government payer policies and reimbursement dynamics

Responsibilities

Lead the development of market access strategies that drive coverage expansion, policy optimization, and quality of access improvements across commercial and government payers for inline and pipeline assets
Identify key differentiators critical to payers for rare disease products in competitive environments and translate into actionable strategy
Anticipate and shape payer dynamics in rare disease to craft clear, differentiated value narratives that resonate in competitive markets
Translate clinical and economic evidence into practical, payer-ready tools that influence coverage and reimbursement decisions
Lead pre-launch payer engagement, value evidence planning, and access readiness to ensure optimal coverage pathways
Partner cross-functionally with medical and marketing to ensure evidence generation aligns to access impact
Engage directly with payer stakeholders to uncover actionable insights and convert them into strategic access decisions
Collaborate with Government Pricing on policy implications such as Medicaid best price, 340B, IRA/GUARD considerations