Clinical Data Manager - Oncology & RWE

1w1 week ago

SOPHiA GENETICS

Bordeaux, FR · Full-time · €55,000 – €75,000

About this role

Are you an experienced and proactive Clinical Data Manager with a strong background in oncology and real-world evidence (RWE)? Join the SOPHiA GENETICS Clinical Operations Team as a Clinical Data Manager of Oncology & Real-World Evidence (RWE) to make a positive impact on cancer and rare disease patients worldwide.

Lead end-to-end data management activities across clinical studies and contribute clinical insight to enhance medical content and study outputs. Interface closely with BioPharma partners in collaborative efforts. Work with clinical operations, medical affairs, and data science teams for high-quality data collection, interpretation, and communication.

Ideally work a hybrid schedule near offices in Bordeaux or Bidart (France) or Rolle (Switzerland), with remote options across EU5 for qualified candidates. Collaborate cross-functionally with biostatistics, medical, regulatory, and business development teams. Ensure data compliance with standards like GPP, GDPR, and FAIR principles.

Directly input into the mission of the cloud-native AI-powered SOPHiA DDM Platform to democratize data-driven medicine. Support internal trainings, study proposals, and discussions with clinical experts and oncologists using data-driven insights. Enable smarter, data-driven decisions in healthcare for patient benefit globally.

Requirements

Degree in Life Sciences, Pharmacy, biology, or equivalent (Master’s or higher preferred)
Minimum 5 years of experience in data management for clinical or real-world studies
Strong clinical background in oncology — ability to interpret clinical context from raw data
Solid understanding of RWE study design, endpoints, and data sources
Experience working in cross-functional, matrix environments
Strong communication skills; able to translate complex data into clear messages for internal and external stakeholders
Fluent in English (written and spoken); French is a plus
Familiarity with CDISC standards, EDC systems, and relevant data privacy regulations is an asset

Responsibilities

Lead end-to-end data management activities for observational and real-world studies in oncology
Define and maintain data management plans, data dictionaries, and quality control processes
Oversee data collection, validation, and cleaning in collaboration with clinical and technical teams
Apply clinical oncology knowledge to ensure meaningful data capture and interpretation
Review and annotate CRFs, ensure consistency of clinical data with study objectives and endpoints
Contribute to the development of medical and scientific content for internal trainings, study proposals, and publications
Support discussions with clinical experts and oncologists by providing data-driven insights and context
Interface with BioPharma partners in the context of collaborative efforts