About this role
The Principal Scientist joins the Cellular Therapy Translational Research group to support cell therapy development programs in autoimmune and inflammatory diseases. This role drives translational development strategies and clinical biomarker plans for BMS cellular therapy clinical studies. The position focuses on advancing next-generation engineered cell-based therapies for hematologic malignancies, solid cancers, and autoimmune disease.
Daily work includes designing and executing translationally focused experiments with contract research organizations and internal and external collaborators. Biomarker identification supports pharmacodynamic evaluation and mechanism of action analyses in the clinical trial setting. The scientist contributes to global regulatory submission activities that advance cellular therapeutics.
The Cell Therapy Thematic Research Center delivers innovative therapies through discovery and translational science at Bristol Myers Squibb. Team members maintain deep expertise in biomarker assays such as flow cytometry, transcriptomics, and proteomics applied to clinical trials. Cross-functional collaboration with biostatisticians and computational biologists ensures timely data analysis and communication.
Bristol Myers Squibb offers balance and flexibility through competitive benefits, services, and programs. Employees gain access to resources that support career growth alongside high-achieving teams in an uncommon scale of opportunity. The environment enables pursuit of goals both at work and in personal lives.
Requirements
- Experienced researcher responsible for driving translational development strategies in cell therapy
- Self-motivated and resourceful in designing experiments with CROs and collaborators
- Deep understanding of biomarker assays including flow cytometry, transcriptomics, and proteomics in clinical trial settings
- Ability to generate and interpret data supporting pharmacodynamic evaluation and mechanism of action
- Experience contributing to global regulatory submission activities for cellular therapeutics
- Proven capacity to develop mechanism of action hypotheses for cell therapy products
Responsibilities
- Develop and implement end-to-end translational research strategies for cell therapy clinical trials
- Partner with biostatisticians and computational biologists to provide timely analysis and communication of data and present its context and impact
- Develop concepts and mechanism of action hypotheses identifying distinguishing characteristics of BMS cell therapy products alone or in combination with other therapies
- Maintain a deep understanding of biomarker assays including flow cytometry, transcriptomics, proteomics and the application and use of these technologies in the clinical trial setting
- Independently manage internal projects in cell therapy drug development
- Serve on internal cross functional project teams and committees as scientific functional lead
- Provide oversight and management of CROs and academic collaborators
- Communicate regularly and prepare and make presentations within the department, externally, and to internal governance committees as required
Benefits
- Wide variety of competitive benefits, services and programs
- Resources to pursue goals both at work and in personal lives
- Balance and flexibility in the work environment
Similar roles
Senior Research Associate - DMPK
20h20 hours agoCytokinetics
US · Full-time · $108,000 – $126,000
Postbaccalaureate Research Associate
20h20 hours agoNationwide Children's Hospital
Dallas, US · Full-time · $42,000 – $55,000
Scientific Project Manager
20h20 hours agoPersonalis
Fremont, US · Full-time · $105,000 – $130,000
Executive Director - Analytical Development & Quality Control
1d1 day agoArdelyx
Waltham, US · Full-time · $267,000 – $327,000