Associate Director - Pharmacology

1w1 week ago

Grifols

Dublin, IE · Full-time · €110,000 – €150,000

About this role

Join Grifols, a global healthcare company since 1909 working to improve health worldwide through plasma-derived medicines and transfusion medicine. The Associate Director, Pharmacology leads non-clinical and early clinical pharmacology strategy across drug development programs. Provides expertise in PK/PD, modeling & simulation, and Model-Informed Drug Development to support dose selection and regulatory submissions.

Lead PK/PD data analysis and modeling using tools like Phoenix WinNonlin and NONMEM. Apply quantitative methods to support non-clinical and early-phase clinical programs. Contribute to regulatory interactions including INDs, BLAs, MAAs, and agency query responses.

Partner cross-functionally with clinicians and statisticians on global teams. Represent Pharmacology on clinical sub-teams and multifunctional groups. Communicate complex concepts to stakeholders and oversee study-level activities like protocol development.

Mentor junior scientists while ensuring scientific excellence and compliance. Design pharmacology plans and drive MIDD strategies. Grifols fosters diversity and equal opportunities in an inclusive environment.

Requirements

Doctoral degree (PhD) or equivalent professional training (PharmD), or post-doctoral experience in clinical pharmacology, pharmacokinetics, pharmacology, toxicology, pharmaceutics, or related discipline
Minimum of 3+ years of relevant industry or academic experience supporting pharmacokinetic, pharmacodynamic, and pharmacology activities across non-clinical and early clinical programs
Hands-on experience contributing to pharmacology strategy and execution in pharmaceutical or biotechnology environments
Proficiency in mechanistic and population PK/PD modeling approaches
Experience with regulatory submissions and interactions such as INDs and BLAs
Ability to apply scientific rigor in fast-paced, collaborative settings

Responsibilities

Lead PK/PD data analysis and modeling activities using Phoenix WinNonlin, NONMEM, and related platforms
Apply quantitative and statistical methods to support non-clinical and early-phase clinical pharmacology programs
Contribute to regulatory interactions and submissions including INDs, BLAs, MAAs, and briefing packages
Provide scientific leadership in matrixed teams driving pharmacology strategy and decision-making
Lead analysis, integration, and reporting of clinical pharmacology data for dose selection
Design and implement pharmacology plans ensuring best practices across project teams
Partner with clinicians and statisticians to optimise dosing strategies and study designs
Drive design and execution of Model-Informed Drug Development (MIDD) strategies