Principal Scientist - Drug Discovery

2w2 weeks ago

MSD

Rahway, US · Full-time · $169,700 – $267,200

About this role

The Principal Scientist, Drug Discovery in the Research and Development Department identifies new molecular entities and technologies for animal health from Company Laboratories or external partners including human pharma, biotech companies, and academia. This role drives advancement of novel targets. The position reports to the Distinguished Scientist and Global Head of Research & Development Liaison and Discovery – Non-infectious Diseases.

The successful candidate leads research programs from ideation through early research, proof-of-concept, and up to the development stage. They interface with researchers and senior management throughout the organization as well as external partners. Responsibilities include operating in a matrix structure to secure resources for Medicinal Chemistry, in vitro Pharmacology, Pharmacokinetics, and other areas.

Daily work involves advancing novel targets in animal health drug discovery within a collaborative matrix environment. The role requires interfacing across departments like Disease Models, Formulation Development, Safety & Toxicology. External collaborations with academia and industry partners are key.

This position offers opportunities to lead programs to development stage and influence global research strategy. It supports progression from ideation to preclinical proof-of-concept in non-infectious diseases. Growth includes managing budgets, contracts, and executive communications.

Requirements

Minimum of 8 years industry or pharmaceutical research experience in drug discovery or preclinical research with a focus on in vivo pharmacology
Advanced and thorough scientific knowledge in pharmacology, disease mechanisms and related preclinical models
Expertise in one of the following fields: oncology, diabetes, respiratory & immunology, cardiology, pain & inflammation, reproduction, drug delivery or biotechnology
Knowledge of regulatory aspects of pharmaceuticals including GLP, GCP and GMP
Ability to manage multiple projects, including budgets, contracts, and timelines
Excellent communication and interpersonal skills
In Vivo Models, Assay Development, Biochemical Assays, Molecular Biology Techniques
10% Travel

Responsibilities

Identify new molecular entities and technologies for use in animal health from Company Laboratories or external partners
Advance novel targets and lead research programs from ideation through early research and proof-of-concept phase up to development
Interface with researchers, senior management throughout the organization, and external partners
Operate within a matrix structure to garner resources for Medicinal and Process Chemistry, in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety & Toxicology
Independently plan, recommend and complete research programs
Manage multiple projects including budgets, contracts, and timelines
Prepare executive level presentations and documents
Prepare patent applications in support of research efforts