About this role
Join Amneal Pharmaceuticals as Senior Executive / Assistant Manager in Pharmacology to design, plan, and perform in-vivo experiments evaluating efficacy and safety of small molecule/biologics drug candidates. Analyze and interpret complex biological data for Hit/Lead selection and optimization. Develop and validate in-vivo/in-vitro model systems for NCE evaluation.
Daily tasks include executing mouse tumor models like Xenograft, handling animal dosing by IP, IV, PO routes, and tissue processing for in-vitro/ex-vivo assays. Utilize statistical tools like GraphPad Prism for data analysis and compound optimization. Prepare detailed reports, technical summaries, and presentations to support project goals.
Collaborate with multidisciplinary teams including synthetic chemists, bioinformatics, pharmacokinetic scientists, molecular biologists, and external CROs. Work in a dynamic environment focused on immuno-oncology and oncology disease areas. Demonstrate expertise in biochemical, cell-based, and analytical assay techniques.
Stay updated with scientific literature and advancements in drug discovery methodologies. Contribute to scientific publications, patent applications, and regulatory documentation. Commit to scientific rigor, innovation, and continuous learning in a diverse, inclusive workplace.
Requirements
- PhD freshers or 1-2 years or master’s with 3-8 years of industry experience in immuno-oncology, pharmacology, biology, or a related field
- Proven experience in drug discovery and development with small molecules/biologics
- Experience with in-vivo pharmacology studies in the disease area of oncology
- Expertise in animal handling includes sampling and dosing by different routes (IP, IV, PO)
- Plan and execute mouse tumor models like Xenograft
- Expertise in tissue processing and in-vitro/ex-vivo assay techniques
- GraphPad Prism or equivalent statistical software for data interpretation and report preparation
- Strong knowledge of biochemical, cell-based, and analytical assay techniques
Responsibilities
- Design, plan, and perform in-vivo experiments to evaluate efficacy and safety of small molecule/biologics drug candidates
- Analyze and interpret complex biological data to Hit/Lead selection and optimization
- Develop and validate in-vivo/in-vitro model systems for evaluation of NCE’s
- Collaborate with multidisciplinary teams including synthetic chemists, bioinformatics, pharmacokinetic scientist, molecular biologist and external CROs
- Utilize statistical tools to support data analysis and compound optimization
- Prepare detailed reports, technical summaries, and presentations
- Stay updated with current scientific literature and advancements in drug discovery methodologies
- Contribute to the preparation of scientific publications, patent applications, and regulatory documentation
Benefits
- Equal opportunity employer
- Does not discriminate based on caste, religion, gender, disability, or any other legally protected status
- Fosters a workplace that values diversity and inclusion
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