GMP Production Chemist

16h16 hours ago

CSBio

Milpitas, US · Full-time · $65,000 – $85,000

About this role

CSBio, a peptide contract manufacturing organization founded in 1993, is seeking qualified individuals to join as GMP Production Chemists at our Menlo Park and Milpitas facilities. This role is responsible for the synthesis and cleavage of peptides or the purification and freeze drying of peptides in our GMP manufacturing areas.

In this position, you will execute batch production records for synthesis and cleavage processes with minimal supervision, analyze organic and inorganic compounds to determine chemical and physical properties, and conduct research on manufactured products to develop and improve product quality. You will also operate laboratory equipment including HPLCs, centrifuges, freeze dryers, and mass spectrometers.

Our team works in a state-of-the-art cGMP peptide production facility that passed an FDA inspection in 2017 and was recommended for commercial drug substance manufacturing. We maintain a clean working environment and contribute to overall lab cleanliness while recording experiments on standardized forms.

CSBio offers opportunities to grow within a company that has expanded its cGMP clinical production capacity as recently as 2023. This role provides hands-on experience in regulated pharmaceutical manufacturing with a focus on quality and continuous improvement.

Requirements

Ability to work on Saturdays and/or Sundays
Excellent communication skills
Ability to work independently and as part of a team
Read work orders thoroughly and have a good understanding of instruction and specification of final products
Prepare and label chemical solutions according to standard formulas
Maintain a clean working environment and contribute to overall lab cleanliness

Responsibilities

Execute batch production records or protocols for synthesis and cleavage processes with minimal supervision in a timely and efficient manner
Analyze organic and inorganic compounds to determine chemical and physical properties
Conduct research on manufactured products to develop and improve product quality
Perform data analysis and review of data for accuracy and completeness
Identify the fully protected 20 amino acids batch by batch in terms of solubility and appearance
Operate laboratory equipment and instruments including HPLCs, centrifuges, freeze dryers, stir plates, lab balances, mass spectrometers, sonicators, vacuum ovens, and N2 tanks
Record purification and other experiments on standardized forms, and check analytical HPLC and mass of dissolved crude peptides properly
Identify target peptide peak by integration and mass spectrometry

Benefits

Medical, dental, and vision insurance (Kaiser HMO or BlueShield PPO; employer pays 90% for employee and 75% for family)
401k with 10% 1:1 match
10 days PTO plus companywide paid holidays during the week of July 4, Thanksgiving (2 days), and the week of December 25
Basic life insurance ($20,000 paid by company) and supplemental life insurance (optional)
Disability insurance (50% standard employer paid)
Carpool, clean air vehicle, and cell phone reimbursement