About this role
Abiologics, Inc. is pioneering Synteins™, a transformational class of macromolecular medicines unlocked by novel synthetic and computational technologies. We seek an experienced Senior Scientist in Medicinal Chemistry specializing in miniprotein and peptide drugs. This role leads projects from early-stage research through clinical development.
Independently plan, execute, interpret, and optimize Syntein structure-activity campaigns through direct, hands-on laboratory work. Implement modern peptide chemistry and conjugation methodologies to accelerate miniprotein drug development optimization. Drive bench-side innovation from concept to reality.
Collaborate with cross-functional teams including computational chemistry, biology, and pharmacology to drive project success. Mentor and guide junior scientists, fostering a collaborative and dynamic laboratory environment. Contribute to patent applications and scientific publications showcasing lab innovation.
Abiologics was founded in Flagship Pioneering’s venture creation engine, originating companies like Moderna Therapeutics. Flagship has fostered over 100 ventures, more than 500 patents, and 50 clinical trials. Join to advance therapeutic modality innovation in biotechnology.
Requirements
- Ph.D. (with a minimum of 5 years of industry experience) or M.S. (with a minimum of 12 years of industry experience) in Medicinal Chemistry, Synthetic Organic Chemistry, Chemical Biology, or related field
- Strong track record of laboratory-based innovation and problem-solving in drug discovery including optimization of affinity, selectivity, drug properties, and PK profile
- Proven expertise in the hands-on peptide synthesis
- Ability to lead and inspire a team of scientists in a dynamic research setting
- Excellent communication skills for both technical and non-technical audiences
- Able to work on-site and attend in-person meetings
Responsibilities
- Independently plan, execute, interpret, and optimize Syntein structure-activity campaigns through direct, hands-on laboratory work
- Implement modern peptide chemistry and conjugation methodologies to accelerate optimization of miniprotein drug development
- Collaborate with cross-functional teams including computational chemistry, biology, and pharmacology to drive project success
- Drive bench-side innovation, ensuring that ideas transition seamlessly from concept to reality
- Mentor and guide junior scientists, fostering a collaborative and dynamic laboratory environment
- Contribute to patent applications and scientific publications, showcasing lab innovation
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