Lead Biologist - Drug Discovery

3w3 weeks ago

Agomab Therapeutics

BE · Full-time · €90,000 – €130,000

About this role

As a Lead Biologist, you will join our early drug discovery and translational sciences team based in Belgium. The team supports early-stage drug discovery programs focused on small molecules with emphasis on disease biology and translational strategies. You will design and coordinate in vitro and in vivo studies with external biology service providers and academic partners.

You will collaborate closely with the Lead Chemist, Project Leader and Project Manager. Responsibilities include integrating and interpreting biological data to contribute to decision-making. You will present insights to internal stakeholders on pharmacology, biomarkers, ADME-DMPK and safety datasets.

Lead biology activities within multi-disciplinary project teams while efficiently outsourcing biology work to CROs. Contribute to CRO selection, contract setup including milestones and budgets with the Research Project Manager. Monitor execution and reporting of experiments with strong input into technical aspects and design.

Work in close interaction with the Project Leader and Lead Chemist on projects. Build correlations like PK/PD relationships to propose next steps and compounds. Enjoy pioneering science in a young biotech with a challenging, innovative and agile environment.

Requirements

PhD in the field of biotechnology or biology (or equivalent experience)
Minimum of ten (10) years of experience in pharmacology in a drug discovery environment
Track record reflecting experience in pharmacology and drug discovery through scientific or patent literature
Experience with tools allowing analysis of pharmacology data, e.g. Excel, GraphPad
Strong knowledge of in vitro and in vivo pharmacology, ADME and DMPK
Pro-active, solution-oriented and performance-driven
Team player with excellent communication, analytical, and organizational skills
Fluent in English, written and spoken

Responsibilities

Lead biology activities within multi-disciplinary project teams
Conduct in vitro and in vivo pharmacological profiling of new molecules
Organize advanced ADME and PK experiments
Integrate diverse datasets including pharmacology, biomarkers, ADME-DMPK and safety
Efficiently outsource biology work to CROs
Contribute to CRO selection, contracts, proposals, milestones and budgets
Monitor execution and proper reporting of experiments
Prepare presentations and present at project meetings and CRO meetings