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MSD

Principal Scientist - Drug Discovery

2w

MSD

Rahway, US · Full-time · $169,700 – $267,200

About this role

The Principal Scientist, Drug Discovery in the Research and Development Department identifies new molecular entities and technologies for animal health from Company Laboratories or external partners such as human pharma, biotech companies, and academia. The successful candidate serves as a key driver to advance novel targets. This role leads research programs from ideation through early research and proof-of-concept phases up to development.

Daily responsibilities include evaluating opportunities from internal and external sources to support animal health innovations. The position interfaces with researchers and senior management throughout the organization, as well as external partners. Professionals operate within a matrix structure to secure resources for essential work areas.

Key support functions encompass Medicinal and Process Chemistry, in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety & Toxicology. The role reports directly to the Distinguished Scientist and Global Head of Research & Development Liaison and Discovery – Non-infectious Diseases. Collaboration spans diverse scientific disciplines in a dynamic pharmaceutical environment.

This position offers opportunities to lead high-impact programs advancing to development stages. Professionals contribute to strategic research initiatives in animal health. The role fosters growth through cross-functional leadership and external partnerships in drug discovery.

Requirements

  • Minimum of 8 years industry or pharmaceutical research experience in drug discovery or preclinical research with a focus on in vivo pharmacology
  • Advanced and thorough scientific knowledge in pharmacology, disease mechanisms and related preclinical models
  • Expertise in one of the following fields: oncology, diabetes, respiratory & immunology, cardiology, pain & inflammation, reproduction, drug delivery or biotechnology
  • Knowledge of regulatory aspects of pharmaceuticals including GLP, GCP and GMP
  • Ability to manage multiple projects, including budgets, contracts, and timelines
  • Ability to independently plan, recommend and complete research programs
  • Excellent communication and interpersonal skills
  • 10% travel

Responsibilities

  • Identify new molecular entities and technologies for use in animal health from internal laboratories or external partners
  • Advance novel targets and lead research programs from ideation through early research and proof-of-concept to development
  • Interface with researchers, senior management, and external partners throughout the organization
  • Operate within a matrix structure to garner resources for Medicinal and Process Chemistry, in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety & Toxicology
  • Independently plan, recommend, and complete research programs
  • Manage multiple projects including budgets, contracts, and timelines
  • Prepare executive level presentations, documents, and patent applications in support of research efforts

Benefits

  • Equal Employment Opportunity employer
  • Commitment to inclusion in hiring process
  • Accommodation available during application or hiring process for US and Puerto Rico residents